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何 林 教授
发布时间:2018-04-13 15:02:36    浏览次数:

 

 

何林,西南大学植物保护学院副院长,教授,博士,博士生导师。中组部“万人计划”领军人才、国家现代农业产业技术体系岗位科学家、科技部“中青年科技创新领军人才”、教育部“新世纪优秀人才”、重庆市“学术技术带头人后备人选”获得者。担任中国昆虫学会理事、重庆市昆虫学会副理事长、重庆市植物保护学会常务理事等学术兼职。主要从事农药毒理与科学应用方面的科研与教学工作,包括有害生物抗药性、农药生物活性、田间药效、环境安全性以及农药新剂型等。尤其在害螨抗药性研究方面具有较深的造诣,已发表相关研究论文70余篇(SCI收录41篇);先后主持国家及省部级科研项目多项;申报国家发明专利8项,已授权4项。 

学习、工作经历

1992.09~1996.07 西南农业大学 本科生;

1996.09~1999.07 山东农业大学 硕士研究生;

2000.09~2003.07 西南农业大学 博士研究生(2001年晋升讲师);

2003.07~2005.07 西南农业大学 副教授(2003年晋升);

2005.07~至今 西南大学 副教授、教授(2009年晋升);

其中:

2004.12~2007.12 中国农业大学 博士后;

2006.07~2007.07 美国奥本大学 访问学者;

2011.03~2011.09 美国奥本大学 高级访问学者。

人才称号

中组部“万人计划”领军人才(2018);

国家现代农业产业技术体系岗位科学家(2017);

科技部“中青年科技创新领军人才”(2016);

教育部“新世纪优秀人才”(2011);

重庆市“学术技术带头人后备人选”(2008)。 

主要科研方向

农药毒理及害虫、害螨抗药性,农药科学使用、除草剂田间药效及安全性评价等。

近5年主持项目

1. 现代农业产业技术体系岗位科学家经费 CARS-21 280万元

2. “入侵种二斑叶螨对本地种朱砂叶螨竞争性扩张的毒理学机制国家自然科学基金项目 3167208565万元

3. “柑橘化学农药协同增效技术及产品研发”  国家重点研发计划子课题项目  2016YFD0200505-2 80万元

4. “朱砂叶螨对阿维菌素靶标抗性的突变鉴定及快速检测研究重庆市基础科学与前沿技术研究重点项目 CSTC2017jcyjBx0061 20万元

5. “AVMs与朱砂叶螨受体-氯离子通道的互作机制研究国家自然科学基金项目 31470115 30万元

6. “GABA量变导致朱砂叶螨对阿维菌素抗性机制研究国家自然科学基金项目(31272059 80万元

7. 农药登记田间药效试验(除草剂)     企业委托  50万元/ 

获奖与发明专利

1. “重庆主要作物除草剂安全使用及药害预警系统开发重庆市科技进步三等奖(2013,排名第一);

2. “朱砂叶螨适应酸雨和杀螨剂胁迫的机理及适合度评估重庆市自然科学三等奖 2009,排名第二);

3. 第三届中国植物保护学会青年科技奖2009);

4. “朱砂叶螨抗药性机理及抗性适合度研究”  重庆市优秀博士学位论文奖(2005);

5. 授权国家发明专利及实用新型专利共5项:

1一种朱砂叶螨P450基因及其应用ZL201510014116.5

2一种包含伊维菌素和丁氟螨酯的杀螨组合物ZL201510040749.3

3一种朱砂叶螨F1538I突变导致的kdr抗性快速检测方法ZL201410006533.0

4“20%伊维菌素毒死蜱水乳剂ZL2009 1 0250855.9

5一种便于害虫监测和防治的诱捕器ZL2012 2 0073769.2

近3年代表性论文

1. Kaiyang Feng, Xiang Wen, Xiulong He, Peng Wei, Li Shi, Yuwei Yang, Lin He*. 2018. Resistant inheritance and cross-resistance of cyflumetofen in Tetranychus cinnabarinus (Boisduval). Pesticide Biochemistry and Physiology, https://doi.org/10.1016/j.pestbp.2018.03.013.

2. Yichao Zhang, Jia Hu, Li Shi, Peng Wei, Zhifeng Xu, Guangmao Shen, Ming Li, Qiang Xu, Lin He*. 2018. A microRNA-1 gene, tci-miR-1-3p, is involved in cyflumetofen resistance by targeting a glutathione S-transferase gene, TCGSTM4, in Tetranychus cinnabarinus. Insect Molecular Biology, doi: 10.1111/imb.12375.

3. Wencai Lu, Yuan Hu, Peng Wei, Qiang Xu, Christian Bowman, Ming Li, Lin He*. 2018. Acaricide-mediated competition between the sibling species Tetranychus cinnabarinus and Tetranychus urticae. Journal of Economic Entomology, doi: 10.1093/jee/toy030.

4. Tian Li, Zhifeng Zhou, Lin He*. 2017. A novel approach for enhancing bacterial strains’ Nitrobenzene degradation rate. International Biodeterioration and Biodegradation, 123: 63-69.

5. Ping Zhang, Qian Yu, Yuhan He, Wentao Zhu, Zhiqiang Zhou, Lin He*. 2017. Chiral pyrethroid insecticide fenpropathrin and its metabolite: enantiomeric separation and pharmacokinetic degradation in soils by reversephase high-performance liquid chromatography. Analytical Methods, 9:4439-4446.

6. Ping Zhang, Wentao Zhu, Dezhen Wang, Jin Yan, Yao Wang, Zhiqiang, Zhou, Lin He*. 2017. A combined NMR- and HPLC-MS/MS-based metabolomics to evaluate the metabolic perturbations and subacute toxic effects of endosulfan on mice. Environmental Science and Pollution Research, 24:18870-18880.

7. Zhifeng Xu, Qiong Wu, Qiang Xu, and Lin He*, 2017. Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite. Toxicological Sciences, 155(1): 258-269.

8. Li Shi, Mengyao Wang, Yichao Zhang, Guangmao Shen, Haishan Di, Yue Wang, Lin He*. 2017. The expression of P450 genes mediating fenpropathrin resistance is regulated by CncC and Maf in Tetranychus cinnabarinus (Boisduval). Comparative Biochemistry and Physiology, Part C. 198, 28-36.

9. Xu Z, Liu Y, Wei P, Feng K, Niu J, Shen G, Lu W, Xiao W, Wang J, Smagghe GJ, Xu Q, He L*. 2017. High gama-aminobutyric acid contents involved in abamectin resistance and predation, an interesting phenomenon in spider mites. Frontiers in Physiology. 8:216.

10. Wencai Lu, Mengyao Wang, Zhifeng Xu, Guangmao Shen, Peng Wei, Ming Li, William Reid, Lin He*. 2017. Adaptation of acaricide stress facilitates Tetranychus urticae expanding against Tetranychus cinnabarinus in China. Ecology and Evolution. 2017; 00: 1–17.

11. Ping Zhang , Wentao Zhu, Dezhen Wang, Jin Yan, Yao Wang, Lin He*. 2017. Enantioselective Effects of Metalaxyl Enantiomers on Breast Cancer Cells Metabolic Profiling Using HPLC-QTOF-Based Metabolomics. International Journal of Molecular Sciences. 2017, 18, 142.

12. Li Shi, Jiao Zhang, Guangmao Shen, Zhifeng. Xu, Qiang Xu*, Lin He*. 2016. Collaborative contribution of six cytochrome P450 monooxygenase genes to fenpropathrin resistance in Tetranychus cinnabarinus (Boisduval). Insect Molecular Biology, 25(5), 653–665.

13. Xing Liu, Guangmao Shen, Haoran Xu, Lin He*. 2016. The fenpropathrin resistant Tetranychus cinnabarinus showed increased fecundity with high content of vitellogenin and vitellogenin receptor. Pesticide Biochemistry and Physiology, 134, 31-38.

14. Yichao Zhang, Zhifeng Xu, Qiong Wu, Miao Peng, Yanchao Liu, Xing Liu, Li Shi, Guangmao Shen, Yu Pan*, Lin He*. 2016. Identification of Differentially Expressed microRNAs between the Fenpropathrin Resistant and Susceptible Strains in Tetranychus cinnabarinus. PLoS ONE 11(4): e0152924.

15. Li Shi, Peng Wei, Xiangzun Wang, GuangmaoShen, Jiao Zhang, WeiXiao, ZhifengXu, QiangXu*, Lin He*. 2016. Functional Analysis of Esterase TCE2 Gene from Tetranychus cinnabarinus (Boisduval) involved in Acaricide Resistance. Scientific Reports. 6, 18646.

16. Peng Wei, Li Shi, Guangmao Shen, Zhifeng Xu, Jialu Liu, Yu Pan*, Lin He*. 2016. Characteristics of carboxylesterase genes and their expression-level between acaricide-susceptible and resistant Tetranychus cinnabarinus (Boisduval). Pesticide Biochemistry and Physiology. 131, 87-95.

17. Yong Li, Zhifeng Xu, Li Shi, Guangmao Shen, Lin He*. 2016. Insecticide resistance monitoring and metabolic mechanism study of the green peach aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae), in Chongqing, China. Pesticide Biochemistry and Physiology. 132, 21-28.

18. Zhifeng Xu, Li Shi, Jianfang Peng, Guangmao Shen, Peng Wei, Qiong Wu, Lin He*. 2016. Analysis of the relationship between P-glycoprotein and abamectin resistance in Tetranychus cinnabarinus (Boisduval). Pesticide Biochemistry and Physiology. 129, 75-82.

19. Li Shi, Jiao Zhang, Guangmao Shen, Zhifeng Xu, Peng Wei, Yichao Zhang, Qiang Xu*, Lin He*.2015. Silencing NADPH-cytochrome P450 reductase results in reduced acaricide resistance in Tetranychus cinnabarinus (Boisduval). Scientific Reports. 5, 15581.

20. Li Shi, Zhifeng Xu, Guangmao Shen, Changgui Song, YingWang, Jianfang Peng, Jiao Zhang, Lin He*. 2015. Expression characteristics of two novel cytochrome P450 genes involved in fenpropathrin resistance in Tetranychus cinnabarinus (Boisduval). Pesticide Biochemistry and Physiology.119, 33–41.

 

联系方式

   址:400716,重庆市北碚区天生路2号,西南大学植物保护学院

   话:023-68251541

  真:023-68251514

E-mail helinok@vip.tom.com

 

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